While War for the Planet of the Apes leaves the door open for additional Planet of the Apes movies to further bridge the gap to the very first Apes film, its primary goal is to close the book on both Caesar’s tale and (most likely) Reeves’ time working on this franchise. War is very much a success in this respect, delivering a great blend of artful cinematic storytelling and popcorn entertainment value – not to mention, yet another awards worthy mo-cap performance from Serkis. Those moviegoers who have found themselves growing disillusioned with summer blockbusters of late, in the wake of subpar sequels and/or hollow “cinematic universe” tentpoles: War for the Planet of the Apes is very much the antidote you’ve been searching for.
Immunohistochemistry showed the expression of PI3K and p-Akt were observed in mononuclear and fibroblast after skin wound, and reached peak in reconstruction. The positive bands of PI3K, p-PI3K, Akt and p-Akt were observed in all time points of the wound healing process by Western blotting. The expression peak of p-PI3K and p-Akt showed in inflammation and proliferation; the expression peak of PI3K and Akt in reconstruction. Real-time PCR showed the expression peak of PI3K mRNA in inflammation and reconstruction and the peak of Akt mRNA in reconstruction.